个人情况介绍、概览

熊志立教授，药物分析学专业博士研究生导师、分析化学专业硕士研究生导师，沈阳药科大学分析化学教研室主任。“分析化学”国家级精品课程、国家级精品资源共享课及省级教学团队的主要成员，辽宁省“分析化学”线上一流课程负责人和沈阳药科大学“分析化学”线上线下混合式一流课程负责人，主讲本科生《分析化学》理论课及实验课。主持辽宁省教改课题2项，主编中国医药科技出版社《分析化学》（第4版），获2020年“辽宁省本科优秀教材”；副主编《分析化学》（第3版）、参编《分析化学》及其配套教材10余部。曾获沈阳药科大学优秀教师、“教书育人”优秀研究生导师等荣誉称号。主持国家自然科学基金面上项目、青年基金项目和其他省、部级课题10余项；在以第一/通讯作者在发表SCI论文50多篇，获授权专利证书2项。

人才称号、社会兼职等

中国药学会高级会员，中国药学会医药生物分析专业委员会委员，中国医药生物技术协会药物分析技术分会青年委员，辽宁省高等学校优秀人才支持计划和沈阳市高层次人才。

主要研究方向

主要从事中药复方药效物质基础和代谢组学研究、药物分析新技术、新方法研究。

纵向项目

1.基于多组学和质谱成像技术构建骨疏丹调控“肠-肾-骨轴”的精准代谢网络，82174235，国家自然科学基金委员会。
2.基于代谢组学的骨疏丹多组分、多靶点整合分析方法研究，81773694，国家自然科学基金委员会。

横向项目

无

论文

1.Dummy molecularly imprinted membranes based on an eco-friendly synthesis approach for recognition and extraction of enrofloxacin and ciprofloxacin in egg samples.Journal of Chromatography A.2021.(IF=4.049)
2.Ultrasound-assisted deep eutectic solvent as green and efficient media for the extraction of flavonoids from Radix scutellariae.New Journal of Chemistry.2019.(IF=3.069)
3.Development and validation of a UHPLC-MS/MS method for the simultaneous determination of five bioactive flavonoids in rat plasma and comparative pharmacokinetic study after oral administration of Xiaochaihu Tang and three compatibilities.Journal of Separation Science.2017.(IF=2.415)
4.A HILIC-UHPLC-MS/MS untargeted urinary metabonomics combined with quantitative analysis of five polar biomarkers on osteoporosis rats after oral administration of .JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2018.(IF=2.813)
5.Systematically characterized mechanism of treatment for lumbar disc herniation based on Yaobitong capsule ingredient analysis in rat plasma and its network pharmacology strategy by UPLC-MS/MS.Journal of Ethnopharmacology.2020.(IF=3.69)
6.Integrated metabolomic analysis for intervention effects of Gushudan on glucocorticoid-induced osteoporostic rat plasma based on RP/HILIC-UHPLC-Q-Orbitrap HRMS.Analytical Biochemistry .2020.(IF=2.877)
7.Deep eutectic solvent combined with ultrasound-assisted extraction as high efficient extractive media for extraction and quality evaluation of Herba Epimedii..JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2020.(IF=3.209)
8.An integrative urinary metabolomic study of the therapeutic effect of Guizhi Fuling capsule on primary dysmenorrheal rats based 1H NMR and UPLC-MS.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2019.(IF=3.209)
9.Magnetic dummy-template molecularly imprinted polymers based on multi-walled carbon nanotubes for simultaneous selective extraction and analysis of phenoxy carboxylic acid herbicides in cereals.Food Chemistry.2020.(IF=6.306)
10.1H-NMR-based urinary metabolomic study on the preventive effects of Gushudan on glucocorticoid-induced osteoporosis rats.Analytical Biochemistry .2020.(IF=2.877)

学术成果

无